The definitive guide to the clinical and scientific aspects of pulmonary medicine-fully updated with the latest advances in the field Fishman's Pulmonary Diseases and Disorders delivers unparalleled coverage of pulmonary medicine. With 2,000+ photos and illustrations, 60 videos, and 18,000 references, this peerless two-volume resource provides a comprehensive overview of the scientific basis of lung function in healthy people and in those with disease. You'll find detailed coverage of the broad array of diseases and disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms, respiratory infections, and respiratory failure. And you'll learn all the latest advances, including molecular development of the lung, stem cells and respiratory disease, genetics of pulmonary disease and the growth of personalized medicine, technical advances in lung transplantation, and many more. Fishman's Pulmonary Diseases and Disorders provides state-of-the-art coverage of the latest topics in critical care medicine, such as early diagnosis and management of sepsis, multiple organ dysfunction syndrome (MODS), acute respiratory distress syndrome (ARDS), management of agitation and delirium in the ICU, and the newly defined entity of "chronic critical illness" New to this edition: *State-of-the-art reviews of the literature made available online *Expanded editorial team provides new perspectives *References streamlined to include only the latest information in pulmonary clinical medicine *Table of Contents revised to highlight the most important areas of concern for clinicians

This issue describes in detail the most current thinking on the way genes affect and determine sleep patterns, behaviors, disorders and needs. ? Sleep researchers continue to study genetic markers that may someday lead to a personalized approach to treatment of sleep disorders. The genetics of restless legs syndrome, narcolepsy, circadian rhythm disorders, obstructive sleep apnea, parasomnias, and insomnia are discussed. A solid understanding of the role genetics and molecular biology play in sleep will aid clinicians in diagnosing and treating these disorders, as well as advising their patients.